Pulse Polio Immunization Campaign

Last update : 14/7/08

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Introduction

 

In pursuance of the World Health Assembly 1988, to eradicate polio by year 2000 AD. The Pulse Polio Immunization, in addition to routine polio immunization, was first started in the year 1995. Every child below 3 years of age was given two doses of oral polio drops with one month apart. In order to accelerate pace of polio eradication, the target age was increased to cover children below 5 years of age from 1996.

 

The modified IPPI (Intensified Pulse Polio Immunization) strategy included vaccination of children through fixed booth approach on first day, followed by extensive house-to-house search of missed children for vaccination. During these years new strategies were introduced to cover endemic states and the results were good. At present mostly the transmission is going in Uttar Pradesh & Bihar. All out efforts are being done to eradicate polio from these high risk areas.

 

Epidemiology of Poliomyelitis

 

Infectious Agent

 

The polioviruses belong to the genus Enterovirus in the family Picornaviridae and comprise three related serotypes: types 1, 2 and 3, all of which can cause paralysis

 

Occurrence

 

In 1988, the year of the WHA resolution calling for global polio eradication, wild polio virus was endemic in more than 125 countries on five continents, paralyzing more than 1000 children every day. As of May 2005, poliomyelitis occurs primarily in Africa & South Asia

It is seasonal occurring more commonly in summer and early autumn in temperate climates. In developing countries with low immunization coverage poliomyelitis produces a significant amount of illness, death & disability

 

Transmission

 

Transmission is primarily person-to-person vial the fecal-oral route. Poliovirus multiplies in the intestines and spread through the feces. The virus is intermittently excreted for up to 2 months or more after infection, with maximum excretion occurring just before paralysis during the first two weeks (14 days) after onset of paralysis.

 

Reservoir

 

Poliovirus is found only in human beings; there is no animal reservoir

 

Communicability

 

Poliovirus is highly communicable. The cases are most infectious one week before and 2 weeks after onset of paralysis. An infected individual will probably infect all other persons in a household and close contacts especially were sanitation is poor.

 

Immunity

 

All unimmunized persons are susceptible to poliomyelitis. Immunity is obtained through wild virus and / or through immunization. Immunity following natural infection (including in apparent and mild infections) or a completed series of immunization with live oral polio vaccine (OPV) results in both humeral and local intestinal cellular responses. Such immunity persists for many years and can serve to block infection with subsequent wild virus.

 

Strategies for polio eradication

 

In May 1998, the World Health Assembly committed the member nations of the World Health Organization (WHO) to achieving the goal of global eradication of poliomyelitis. This goal is defined as:

  • No cases of clinical poliomyelitis associated with wild polio virus, and

  • No wild poliovirus found worldwide despite intensive efforts to do.

 

The following strategies to achieve polio eradication were adopted by the WHO for worldwide implementation in all polio-endemic countries:

 

Achieving and maintaining high routine coverage in infants younger that 1 year with at least 3 doses of oral polio vaccine (OPV3): Paralytic polio can be caused by any 3 closely-related strains (serotypes) of poliovirus. Trivalent OPV (tOPV) provides immunity against all 3 types. Three routine trivalent OPV should be received by infants at ages 6, 10 and 14 weeks. WHO & UNICEF also recommend that all newborns receive a dose of trivalent OPV at birth (birth dose of OPV)

 

Administering supplemental doses of OPV to all children aged<5 years during national immunization days to rapidly interrupt transmission: National Immunization Days (NIDs) in which a dose of OPV id administered to all children in the target age group, regardless of previous vaccination history. Subsequent doses are administered in the same way after an interval of 4-6 weeks from the previous round. India the term for NID is Pulse Polio Immunization (PPI). PPI rounds are often planned during the low transmission session when conditions are optimal to .to interrupt the remaining chains of poliovirus transmission. In addition to protecting vaccinated children, massive use of OPV probably also results in secondary spread of shed virus, further amplifying the effect of mass OPV administration and facilitating interruption of wild polio virus transmission.

 

Surveillance of Acute Flaccid Paralysis cases: This is done to identify all reservoirs of wild polio virus transmission. This includes reporting of ALL AFP cases, investigation them and laboratory resting of all stool specimens collected from such cases for polio viruses in specialized laboratories.

 

Conduction mop-up vaccination campaigns: When poliovirus transmission has been reduced to well defined and focal geographic areas, intensive house-to-house, child-to-child immunization campaigns are conducted over a period of days to break the final chains of virus transmission.

 

Polio Vaccine

 

The live attenuated oral polio vaccine (OPV), which was used in mass campaigns in 1959. In developing countries OPV is the vaccine of choice, not only because of case of administration but also because it simulates natural infection, induces both circulating antibody and intestinal immunity and by secondary spread, probably protects susceptible contacts. OPV is the vaccine recommended for polio eradication

 

It has been well documented that the use of OPV can successfully interrupt wild poliovirus transmission in both industrialized and developing countries.

 

Logistics

 

Cold chain is very important component in the implementation of IPPI campaign. Cold chain equipments and other logistics e.g. Cold boxes, Vaccine Carriers and Ice Packs are available in sufficient number but Walk-in-Freezers (WIFs) and Walk-in-Coolers (WICs) supplied in year 1986 needs replacement and small deep freezer / large deep freezer require for the prepare sufficient ice packs for districts.

 

AFP Surveillance

 

The goal of polio eradication is to achieve zero case-status of poliomyelitis associated with the wild polio virus. In year 2001 there was no positive case in state but in year 2002, 21 cases and in year 2003, 11 cases were reported. The last case was from district Sehore and the month of onset was November 2003. Since then Madhya Pradesh has not detected any case inspite of good surveillance and maintaining a free state.

 

National Polio Surveillance Project (WHO)

 

The National Polio Surveillance Project is a collaborative project of Govt. of India & the World Health Organization and managed by the latter. Currently a team of more than 250 Surveillance Medical Officer (SMO), Sub-Regional Coordinator (SRC) and Regional Coordinator (RC) are spread across the country who comprise the field staff of project. They are supported by a network of 09 Polio National Laboratories, which undertake the Virological Investigation of AFP (Acute Flaccid Paralysis) cases. The central headquarter unit of the project – The National Polio Surveillance Unit (NPSU) provides logistical & technical backup to the field staff.

 

In October 1997, active surveillance of Acute Flaccid Paralysis was established to meet the demands of Polio Eradication. SMOs with Government counterparts established Reporting Units for reporting of occurrence of AFP cases to the District, State & National levels Timely Case Investigation & collection of stool specimen form AFP cases and its shipment to laboratories. AFP Surveillance at the local level is institution based through a comprehensive network of reporting sites which includes health facility reporting units & informers. As of 2005 approximately 9500 reporting units & approximately 12,300 informer units have been enrolled under the AFP surveillance network throughout the country. By ensuring reporting of all AFP cases from the above sources, the DIO/SMO aims to capture all AFP cases occurring in his area.

 

SMOs Network

 

In Madhya Pradesh there are total 15 SMOs including SRC & State SMO at Bhopal. SMOs are providing extensive training to government counterparts, helping in planning for Supplementary Immunization Activities (SIAs) and maintaining AFP surveillance at highest level.

 

Sr

No.

Name and address

District covered

Telephone

Fax

Mobile

1

Dr. Ravindra Banpel

2nd floor,Health Section

Directorate of Health Services

West Wing,

Satpuda Bhawan, Bhopal                                    

Entire MP

0755 - 2571104, 2577762, 2577768

0755-2571108

98268-08565

2

Dr.O P Tiwari      

SMO, NPSP - unit Bhopal 

131/13, Andhra Bank Building, 

M P Nagar Zone II, Bhopal (MP)

Bhopal, Sehore & Hoshangabad

0755-2761486

0755-2761487

98262-56090

3

Dr. Vinay Kr Bhai

MO, NPSP- unit Shahdol 

IPP-6 Training Centre

District Hospital Campus,

Shahdol-484001 -(MP)

Shahdol, Dindori, Umaria and Anooppur

07652-248713

07652-248712

94251-80823

4

Dr. Bhupesh Kori

SMO,NPSP- unit Jabalpur, Ground floor,

Department of Paediatrics, NSCB Medical College, 

Jabalpur-482001-(MP)

Jabalpur, Katni, Mandla and Narsinghpur

0761-2370271

0761-2370418

94253-25376

5

Dr.

SMO, NPSP- unit Rewa  

3rd floor, PSM department, 

S. S. Medical College ,  Rewa                               

Rewa ,Satna and Sidhi

07662-255229

07622-255230

 

6

Dr. Parag Shah

SMO, NPSP- unit Gwalior 

Room no.3 ,Department of

Community Medicine,

G R Medical College,

Gwalior-474009 (MP)

Gwalior , Datia and Shivpuri

0751-2338803

0751-2338804

94254-07667

7

Dr.Santosh Shukla

SMO, NPSP-unit Sagar

O/O C.M & H.O.,Danida Building

Room no.7, Tili Hospital, Tili  

Sagar-470001

Sagar , Raisen and Damoh

07582-236461

07582-236580

94251-93964

8

Dr. Arun G Katkar

SMO, NPSP-unit Indore 

Health & Family Welfare Training Centre,

CRP Lines, Behind M Y Hosp.

Indore-452001 ( MP)

Indore, Ujjain, Shahjapur and Dewas

0731-2528645

0731-2528646

98260-44883

9

Dr. Sandeep Sangle

SMO, NPSP-unit Guna 

1st floor, Civil Surgeon Office,

District Hospital Campus 

Guna-473001

Guna, Vidisha and Rajgarh and Ashok Nagar

07542-251127

07542-251115

94253-10048

10

Dr. Sushil Wakchaure

SMO , NPSP- unit Balaghat 

Old X-Ray room, Near Bus stand,

 Balaghat-481001

Balaghat, Seoni and Chindwara

07632-240565

07632-241565

94258-22410

11

Dr. J M Gandhi 

SMO, NPSP- unit Chhattarpur

CM & HO Office Opp. Maharaja College,

Chhattarpur-471001

Chhattarpur, Tikamgarh and Panna

07682-244465

07682-244467

98263-23295

12

Dr. V P Vaidya  

SMO, NPSP-unit Betul  

District Training Centre,

IPP6  Bld, 2nd Floor,

Hospital Campus,

Near Nehru Park Betul

Betul, Harda , Khandwa, and Burhanpur

07141-232414

07141-232413

94253-04214

13

Dr. O P Tiwari 

SMO, NPSP-unit Ratlam

Ist floor Bal Chikitsalaya

GPO Road Ratlam-457001

Ratlam, Mandsaur, Neemuch and Jhabua

07412-221960

07412-220859

94253-29190

14

Dr. D G Chavhan

SMO, NPSP- unit Khargone   

Ist Floor, Old Eye Ward,

Sanawad Road,  Khargon

Barwani, Dhar and Khargone

07282-244008

07282-244009

94253-27058

15

Dr.Anup Gurha

SMO, NPSP- unit Morena

Civil Hospital Campus, Morar,

Gwailor - 474006

Morena, Bhind and Sheopur

0751-2663046

0751-4032124

94253-09029

 

State Indicator

Comparison in Year (Madhya Pradesh)

Indicator

Year

2000 2001 2002 2003 2004 2005 2006 2007 2008* 

Total AFP Cases

632 383 497 548 772 1141 1397 2145 876

Virus Positive

2 0 21 11 0 0 3 0 0

Compatible

13 13 24 29 25 14 14 10 0

AFP Rate

2.01 1.58 2.02 2.16 2.98 4.3 5.15 7.74 5.83

N.P AFP Rate

1.96 1.53 1.84 2.00 2.88 4.25 4.91 7.70 4.69

Adeq. Stool (%)

86 85 82 78 79 81 76 82 82

                                                                                                                                 * As on 30/06/2008